Two sample MR report
RPS26_Dendritic Cell (DC) against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 13 | 0.0710268 | 0.2464805 | 0.7785783 |
| Weighted median | 13 | 0.1658679 | 0.0163837 | 0.0000000 |
| Inverse variance weighted | 13 | 0.1264839 | 0.0343501 | 0.0002312 |
| Simple mode | 13 | 0.1825728 | 0.0182676 | 0.0000004 |
| Weighted mode | 13 | 0.1769503 | 0.0173490 | 0.0000003 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 129.3153 | 11 | 0 |
| Inverse variance weighted | 129.9232 | 12 | 0 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0331634 | 0.1458333 | 0.8242792 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0013769 | 1.4e-06 | TRUE | 0.0006075 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
